Metabolomics Postdoctoral Associate

Metabolomics Postdoctoral Associate

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Metabolomics Postdoctoral Associate

Biotechnology Resource Center Proteomics and Metabolomics Facility

Cornell Institute of Biotechnology - Research Division

This postdoctoral associate will assist the Director of the BRC Proteomics and Metabolomics Facility in the development and implementation of various sample preparation techniques and LC-/MS/MS techniques for metabolomics/lipidomics analysis, and subsequent MS data interpretation. The Proteomics and Metabolomics Facility is a Biotechnology Resource Center Service Facility that provides fee-for-service access to advanced technologies in protein and metabolite separations, identification and characterization of proteins and small molecules in complex biological samples through Liquid Chromatographic Mass Spectrometry.  Customers of the facility include faculty, staff and students from Cornell University, Weill Cornell Medicine, and external non-profit and for-profit institutions. The position will be part of a high-energy, cutting-edge Proteomics and Metabolomics Facility team and requires the ability to participate in multi-disciplinary research in a collaborative setting.

The incumbent in this position is responsible for LC-MS/MS analyses on a variety of samples prepared from complex biological sources, operation and maintenance of advanced LC-MS instruments, as well as several untargeted metabolomics/lipidomics-based database search engines and bioinformatics tools. The incumbent will need a strong organic chemistry background, and have significant knowledge of small molecule/drug metabolism with basic metabolic reactions, and MS-associated bioinformatics tools for untargeted metabolomics, identifications and targeted small molecule profiling. The incumbent will need to possess excellent MS data interpretation skills for interpretation of mass spectra for structural elucidation, and be able to routinely perform post-MS analysis data interpretation for customers. The incumbent in this position will be required to develop standard operating and quality assurance procedures covering sample preparation and multiple LC separation technologies for variable metabolomics samples, and to provide consultation on metabolomics project design and data analysis.

Additionally, this position will write a variety of technical and/or project reports for facility users and collaborative PIs. The incumbent is expected to contribute to the preparation of publications and grant proposals.  Strong oral and written communication skills are required. In addition, the incumbent is required to keep a detailed laboratory notebook, contribute to general orderliness of the laboratory and support lab health and safety compliance.

What we need:

  • PhD in Biochemistry, Chemistry, Biology or related discipline with at least two years LC-MS experience with demonstrated understanding of current metabolomics technologies.
  • Strong work ethic and self-motivation. 
  • Excellent communication, attention to detail, and organizational skills.
  • Proficient computer skills and experience with Microsoft Office.

Additional qualifications that would be extra helpful for the position:

  • Previous experience on operation of Thermo’s UltiMate3000 LC system and Orbitrap mass spectrometer.
  • Knowledge of Compound Discoverer and LipidSearch software tools.
  • Previous experience on SciexOS software.

Postdoctoral associates are appointed in 1-year terms, with renewal contingent on continued funding and successful performance.

Benefits and reward include:

  • Comprehensive health care options, generous retirement contributions, access to wellness programs, and employee discounts with local and national retail brands, and more.
  • Our leave provisions include three weeks of vacation and 13 holidays: Martin Luther King, Jr. Day, Memorial Day, Juneteenth, Independence Day, Labor Day, Thanksgiving and the day after, and an end of the year winter break from December 25-January 1.
  • Impressive educational benefits include access to a plethora of professional development courses, tuition-free Part-Time Study, Employee Degree Program, heavily discounted eCornell courses and certificate programs, tuition aid for external education, and Cornell Children's Tuition Assistance Program.

To apply for this opportunity, please submit a cover letter and CV to Dr. Sheng Zhang at


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For general questions about the position or the application process, please contact the Recruiter listed in the job posting or email

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Diversity and Inclusion are a part of Cornell University’s heritage. We are a recognized employer and educator valuing AA/EEO, Protected Veterans and Individuals with Disabilities. We also recognize a lawful preference in employment practices for Native Americans living on or near Indian reservations. Cornell University is an innovative Ivy League university and a great place to work. Our inclusive community of scholars, students, and staff impart an uncommon sense of larger purpose, and contribute creative ideas to further the university's mission of teaching, discovery, and engagement.


About Us

Cornell University is an innovative Ivy League university and a great place to work. Our inclusive community of scholars, students and staff impart an uncommon sense of larger purpose and contribute creative ideas to further the university's mission of teaching, discovery and engagement. With our main campus located in Ithaca, NY, Cornell's far-flung global presence includes the medical college's campuses on the Upper East Side of Manhattan and Doha, Qatar, as well as the Cornell Tech campus located on Roosevelt Island in the heart of New York City.

We offer a rich array of services, programs and benefits to help employees advance in their career and enhance the quality of personal life, including: employee wellness, workshops, childcare and adoption assistance, parental leave, flexible work options.