he Lewis Laboratory in the Nancy E. and Peter C. Meinig School of Biomedical Engineering at Cornell University (Ithaca, NY) is seeking a creative, self-directed Postdoctoral Associate to develop intravital imaging and three-dimensional immunolabeling approaches for studying neural regulation of osteocyte mechanotransduction. The Lewis Lab (https://www.kjlewislab.com) develops intravital imaging approaches to interrogate novel concepts in bone mechanotransduction.
In this position, you will take ownership of developing and applying two complementary methods: multiphoton imaging of osteocyte signaling during mechanical loading in vivo, and whole-mount immunohistochemistry to map cholinergic nerve fibers in relation to osteocytes in intact bone. You will combine these methods with mechanical loading and genetic, pharmacological, and optogenetic approaches to determine how neural signals change which osteocytes respond to force, and whether those cellular responses contribute to long-term skeletal adaptation.
Responsibilities
Qualifications
Required:
Preferred:
About Cornell and the Lewis Lab
Cornell University is an Ivy League institution located in Ithaca, NY. The Meinig School of Biomedical Engineering brings engineers, life scientists, and clinicians together in a collaborative environment where fundamental biology and engineering approaches inform one another. Cornell’s research infrastructure includes the Biotechnology Resource Center Imaging Facility, with multiphoton, confocal, light-sheet, and micro-CT imaging, as well as engineering resources for biomechanics, design, and fabrication. The Lewis Lab develops intravital imaging approaches to interrogate novel concepts in bone mechanotransduction and tissue cross-talk. This project focuses on communication between bone and the nervous system, asking how cholinergic signaling tunes osteocyte mechanosensitivity and skeletal adaptation.
How to Apply
Qualified applicants should submit 1) a cover letter summarizing their background, qualifications, and interest in the position, 2) a curriculum vitae, and 3) names and contact information for three references.
Materials should be submitted online at: https://academicjobsonline.org/ajo/jobs/33428. Applications will be accepted until the position is filled.
Inquiries may be directed to: Professor Karl Lewis, kjl235@cornell.edu.
Pay Range:
$62,232.00 - $88,745.00
Pay Ranges:
The hiring rate of pay for the successful candidate will be determined considering the following criteria:
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